29th March 2019, 16:42 | ChallengeCup
Thatto Heath Crusaders v North Wales Crusaders | Saturday | 2.30pm | Live on Our League
Broadcast exclusively live on Our League, the battle of the Crusaders at Thatto's Crusader Park pits the National Conference League big guns at home to Betfred League 1 outfit North Wales.
The pair have gone head-to-head twice in pre-season games previously, with North Wales coming out on top both times.
However, North Wales are yet to claim a league win in 2019 and sit ninth in the third tier. Meanwhile, Thatto Heath have won both of their league fixtures this year and are sit fourth in the fourth tier.
Could the amateurs topple the semi-pros this weekend?
Keighley Cougars v Beadford Bulls | Sunday | 2.45pm | Live on BBC Sport
Shown on the BBC Red Button and BBC Sport website, these local rivals locked horns twice in Betfred League 1 last year with the Bulls claiming comfortable wins on both occasions.
But Bradford have been ravaged by injuries this year and sit seventh in the Betfred Championship having won four of their eight league games in 2019.
And Keighley, who have two wins from four in League 1, can call on home advantage and a largely fit squad.
Last season was the first time the pair had met in a competitive match for almost 30 years.
The Cougars last beat Bradford way back in 1945, 5-0 in a Challenge Cup semi-final first leg - can they conjure up the spirit of '45?
Oldham v Widnes Vikings | Sunday | 3pm
Another battle in the North West sees Widnes travel to Oldham for the right of a place in Round 5 of the Coral Challenge Cup.
Hosted at Bower Fold, home of Stalybridge Celtic, Oldham have history of overcoming full time opposition - they famously stunned Hull KR 36-22 away from home to reach the last 16 three years ago - and will come into Sunday's game with confidence having won three of their four fixtures so far this season.
But revived Widnes are riding the crest of a wave recently - they wiped out their -12 points for entering administration last weekend and were only outdone by Toronto Wolfpack in February, giving them an admirable 7-1 record in the Betfred Championship.
Oldham last took on Widnes in February 2009, when they claimed something of a scalp in winning 22-20 in the Northern Rail Cup second round.
Hunslet v Halifax | Sunday | 3pm
A West Yorkshire derby at the South Leeds Stadium, Halifax head into this game having won their last seven away meetings with Hunslet.
Hunslet's last home victory against Halifax was a 13-6 Lager Championship win at Elland Road in November 1984.
Betfred Championship outfit Halifax will be favourites for the tie, but will have to be on their guard on Sunday.
'Fax have lost their last two, while Hunslet have set League 1 alight in 2019 - winning all four of their games and sitting top of the table.
Will Hunslet have what it takes to reach Round 5?