Wales captain Ffion Lewis' second-half hat-trick was not enough to deny Ireland victory in their historic first Women's Rugby League international in Colwyn Bay.
Lowri Norkett scored the opener for Wales and they led through Eleri Michael, after Clodagh Dunne had scored Ireland's first-ever try.
Bettie Lambert's try and Syphonia Pua's conversion put Ireland 10-8 ahead.
Ireland's Stacey Greenwood, Storm Cobain and Alex McGuinness also crossed while Lewis (3) and Norkett replied.
But the hosts' tally of six tries to five was no consolation for missing all their conversion attempts.