Leigh Miners Rangers will begin their defence of the Conference Challenge Trophy with a home game against Hunslet Club Parkside.
Fellow Premier Division sides Rochdale Mayfield and Wigan St Patricks also have home advantage after been drawn to face Bradford Dudley Hill and Rylands Sharks respectively.
The draw also threw up two West Yorkshire derbies with Thornhill Trojans facing Stanningley and Elland making the trip over to Leeds to take on Hunslet Warriors.
Milford Marlins were given a bye into round two.
Conference Challenge Trophy: Round One
Stanley Rangers v Thatto Heath Crusaders
Rochdale Mayfield v Bradford Dudley Hill
Leigh Miners Rangers v Hunslet Club Parkside
Leigh East v West Hull
Normanton Knights v Oldham St Annes
Waterhead Warriors v East Leeds
Thornhill Trojans v Stanningley
Wigan St Patricks v Rylands Sharks
Saddleworth Rangers v Crosfields
Drighlington v Gateshead Storm
Millom v Featherstone Lions
Hunslet Warriors v Elland
Underbank Rangers v Skirlaugh
Dewsbury Celtic v Wigan St Judes
Ince Rose Bridge v Dewsbury Moor Maroons
All ties scheduled to be played on Saturday April 30.